A low intensity conflict lasting 3 years from 2270 to 2272.
The Federation in the form of Starfleet objected, strongly and set out to defend all three systems. The Orion Colonies washed their hands of him. Three years later with the war threatening to spill into the Orion Colonies and a general conflict the Orion Syndicate assassinated Botock to stop the war.
The war resulted in the destruction of Boctock's house, and the loss of three Starfleet vessels, all three of them Ane built Emerald class frigates. The two independent worlds were driven into the arms of the Federation by Botock's efforts.